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Secondary endpoints at week 12 included at least a 75 or 90 percent improvement in psoriatic skin lesions, as measured by PASI 75 or PASI 90, and improvement in quality of life, as measured by the Children’s Dermatology Life Quality Index (CDLQI) [patient-reported outcome]. Read More A Phase 3 study, CADMUS Jr, is currently ongoing to evaluate the efficacy and safety of STELARA in the treatment of pediatric patients 6 to 11 years of age living with moderate to severe plaque psoriasis. About STELARA (ustekinumab) STELARA is a human interleukin (IL)-12 and IL-23 antagonist indicated in the U.S. for the treatment of adult patients with: moderate to severe plaque psoriasis who are candidates for phototherapy or systemic therapy; active psoriatic arthritis, alone or in combination with methotrexate; and moderately to severely active Crohn’s disease who have failed or were intolerant to treatment with immunomodulators or corticosteroids but never failed treatment with a tumor necrosis factor (TNF) blocker, or who failed or were intolerant to treatment with one or more TNF blockers. The Janssen Pharmaceutical Companies of Johnson&Johnson maintain exclusive worldwide marketing rights to STELARA, which is currently approved for the treatment of moderate to severe plaque psoriasis in 88 countries, active psoriatic arthritis in 75 countries, pediatric psoriasis in 38 http://tylerramirezsafe.boxcrack.net/2016/07/27/the-following-tips-will-help-you-choose-your-approach-to-boost-your-platform-score-plan-your-introductions-introductions-deserve-more-than-impromptu-fumbling countries and moderately to severely active Crohn’s disease in 32 countries. IMPORTANT SAFETY INFORMATION STELARAis a prescription medicine that affects your immune system. STELARAcan increase your chance of having serious side effects including: Serious Infections STELARAmay lower your ability to fight infections and may increase your risk of infections. While taking STELARA, some people have serious infections, which may require hospitalization, including tuberculosis (TB), and infections caused by bacteria, fungi, or viruses. Your doctor should check you for TB before starting STELARAand watch you closely for signs and symptoms of TB during treatment with STELARA. If your doctor feels that you are at risk for TB, you may be treated for TB before and during treatment with STELARA. You should not start taking STELARAif you have any kind of infection unless your doctor says it is okay.
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Only nine weeks after surgery, the formerly conjoined twins have moved to Blythedale Childrens Hospital, a rehab facility, to start the next phase of their recovery. This is a bittersweet day for us, mom Nicole McDonald said in a statement. We are so proud of the strength our boys show us every day as they progress in their recovery, and we are looking forward to seeing them thrive in rehab, but the people at Montefiore have become our extended family. Related : Formerly conjoined twins recovering, gaining mobility after separation The 15-month-old twins were born conjoined at the head, which is also known as craniopagus twins. This rare occurrence affects one out of every 2.5 million births and almost half, 40 percent, are stillbirths. Nine weeks ago, a team 40 medical staff led by Dr. James Goodrich director of pediatric neurosurgery at Childrens Hospital of Montefiore in the Bronx separated the twins in an arduous 27-hour surgery. Since then, the twins made a stunning recovery. “Nine weeks is an exceptionally short time for what they underwent and it exceeds all of our hopes and expectations,” Dr. Oren Tepper, a plastic surgeon who led the team that reconstructed the twins’ skulls, told TODAY. Even though the boys made a strong recovery, they faced challenges. Both suffered infections and Anias experienced seizures, a common side effect of the surgery, which involved cutting into brain tissue to separate them.
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